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Glyxambi 
Description
Generic Name: empagliflozin and linagliptin
Drug Class: sodium-glucose co-transporter 2 (SGLT2) inhibitor and dipeptidyl peptidase-4 (DPP-4) inhibitor
Indications
Glyxambi is an oral prescription drug used to improve glycemic control among adults with type 2 diabetes mellitus when treatment with empagliflozin and linagliptin is necessary. It is also used to reduce the risk of cardiovascular mortality among patients with type 2 diabetes and established cardiovascular disease.
Dosage Forms
This is available in Glyxambi 25 mg / 5 mg and 10 mg / 5 mg tablets.
Glyxambi Mechanism of Action
This is a combination product of an SGLT2 inhibitor and a DPP-4 inhibitor. First, it reduces the reabsorption of filtered glucose from the tubular lumen and lessens the renal threshold of glucose, resulting in an increase in urinary glucose excretion. Second, it slows the inactivation of incretin hormones. By prolonging and increasing the levels of active incretin hormones, insulin release is increased, and glucagon levels in the circulation are decreased in a glucose-dependent manner.
How to Take Glyxambi
Before taking Glyxambi, it is necessary to read the information leaflet or medication guide given by a healthcare professional. Do not take medicine unless you understand the usage and instructions. Ask your doctor or pharmacist for further medical advice or additional details.
This tablet is only meant to be taken by mouth. This is usually prescribed once a day, preferably in the morning. This medicine is suitable for consumption with or without meals. Swallow the entire tablet and immediately drink the liquid. Cutting or crushing this product is not recommended.
Make a dosing schedule. Do not increase or decrease your Glyxambi dosage. You should also not take this oral drug more frequently than advised.
This diabetes medication is only an adjunct to proper diet and regular exercise. It may not work as well if lifestyle changes are not applied. Always eat a healthy balanced meal and do exercise regularly.
Glyxambi Side Effects
Mild & Common Side Effects:
-Dizziness
-Lightheadedness
-Frequent urination
Severe Side Effects:
-Painful or urgent urination
-Pink-tinged urine
-Changes in urine output
-Unusual skin blisters
-Unusual tiredness
-Shortness of breath
-Swelling ankles or feet
-Sudden weight gain
-Severe abdominal pain
-Persistent nausea and vomiting
-Yeast infection in the vagina or the penis
-Fournier’s gangrene
-Low blood sugar
-High blood sugar
-Dehydration
Note that this is not a full/complete list of the side effects of Glyxambi.
If you experience severe or persistent side effects, refrain from taking the drug and contact your doctor.
Warnings and Precautions
Do not take this prescription drug if you have a known allergy to empagliflozin, linagliptin, or any inactive ingredients the tablet may contain. Always be aware of signs of a serious allergic reaction, such as dyspnea, swelling of the face and throat, severe dizziness, swollen lymph nodes, hives/itching, and skin rash. If this happens, stop taking this oral medication and see a doctor immediately.
Glyxambi may be contraindicated for people with a history of pancreatitis, kidney disease, dehydration, gallstones, high cholesterol, yeast infection, heart failure, alcohol abuse, and dehydration. Also, due to possible drug interactions, first discuss with your doctor all the prescription medications, nonprescription medications, supplements, and herbal products you are taking.
Among the commonly experienced when the blood sugar is too high or too low are dizziness, drowsiness, and blurred vision. When doing tasks that need alertness and clear vision, practice safety caution
Restrict your intake of alcoholic beverages. Alcohol can trigger certain adverse effects. It can also increase the risk of low blood sugar or hypoglycemia and high ketone level.
Pregnant and breastfeeding moms must not take this drug unless it is extremely necessary. Talk to your healthcare provider about all the possible risks. Additionally, pregnancy can either cause or worsen diabetes. Talk to the doctor about changes in the treatment plan.
How much does Glyxambi cost?
You may check the list of prices on this page. To get the best deals, purchase it from Pharmapassport.
Frequently Asked Questions (FAQs)
What is Glyxambi used for?
Glyxambi (empagliflozin & linagliptin) is used to treat type 2 diabetes mellitus. It can also reduce the risk of cardiovascular deaths among adults who have type 2 diabetes and have been clinically diagnosed with cardiovascular disease.
What is Glyxambi drug class?
This diabetes medication has two classifications. It is a combination of a sodium-glucose co-transporter 2 inhibitor and a dipeptidyl peptidase-4 inhibitor.
How much Glyxambi can you take?
This combination drug is only prescribed once daily. Do not administer it more frequently than prescribed.
Can I take Glyxambi and metformin together?
There are no established interactions between Glyxambi and metformin. It is safe to take these antihyperglycemic drugs together.
Does Glyxambi make you lose weight?
Yes, there is a link between Glyxambi & weight loss. Patients taking this drug are reported to lose three percent of their total body weight.
Is Glyxambi available in generic?
Presently, no generic alternatives are available for this medication. If this drug is not working for you, you must notify your physician.