Description
Generic Name: dabigatran etexilate mesylate
Drug Class: direct thrombin inhibitor
What is Pradaxa?
Pradaxa (generic name: dabigatran etexilate mesylate) is an oral prescription drug used to reduce the risk of systemic embolism and/or stroke among patients with non-valvular atrial fibrillation. It is also used to treat deep vein thrombosis or pulmonary embolism and reduces the risk of recurrence.
Dosage Forms
This is available in Pradaxa 75 mg, 110 mg, and 150 mg capsules.
Pradaxa Mechanism of Action
This anticoagulant works by facilitating the conversion of fibrinogen into fibrin while on the coagulation cascade. It also prevents the development of thrombus.
How to Take Pradaxa
Before starting to use this medication, it is necessary to read the information leaflet or medication guide given by a healthcare professional. You must not take any medication unless you have understood the uses and directions. Ask your doctor or pharmacist for further medical advice or additional details.
This capsule is only meant to be taken by mouth. This is usually prescribed twice a day, with or without a meal. Once you experience stomach upset after taking this drug, take it with food. Swallow the medication and drink a full glass of water (8 ounces) right after. Do not chew, crush, or divide the capsule.
Make a dosing schedule. Do not increase or decrease your Pradaxa dosing. You should not also take this oral drug more frequently than advised.
Pradaxa Side Effects
Mild & Common Side Effects:
-Nausea
-Indigestion
-Diarrhea
-Upset stomach
-Easy bruising
-Heartburn
Severe Side Effects:
-Unusual pain or swelling
-Prolonged or unusual bleeding
-Frequent nosebleeds
-Severe headache
-Fainting
-Unusual weakness
-Severe vomiting
-Abdominal pain
-Dark urine
-Fatigue
Note that this is not a full/complete list of the side effects of Pradaxa.
If you experience severe or persistent adverse reactions, discontinue medication and call your doctor or healthcare professional.
Warnings and Precautions
Do not take this prescription drug if you have a known allergy to dabigatran or any inactive ingredients it may contain. Always be watchful for any signs of serious allergic reactions, including trouble breathing, swelling of the face and neck, severe dizziness, swollen lymph nodes, hives/itchiness, and skin rashes. If this occurs, stop taking this oral medication and seek emergency medical help immediately.
This medication may be contraindicated for people with a history of bleeding problems, kidney disease, liver disease, blood disorders, stroke, and antiphospholipid syndrome. Also, due to possible drug interactions, you should discuss all the prescription medications, nonprescription medications, supplements, and herbal products you are taking.
This oral medication is known to increase the risk of bleeding. When using sharp objects, such as razors, knives, and nail cutters, you must practice safety caution. You should also try to avoid contact sports or any similar activities that can cause bruising and bleeding. Intramuscular injections should also be avoided as much as possible.
Pregnant moms should avoid this oral drug as it can increase the risk of bleeding for the pregnant woman and the baby. For breastfeeding moms, it is unknown if it can pass into breast milk. Talk to your healthcare provider about all the possible risks.
Frequently Asked Questions (FAQs)
1.Is Eliquis and Pradaxa the same?
These drugs are both anticoagulants. On Pradaxa vs. Eliquis, both work well in reducing blood clots and the risk of stroke and systemic embolism.
2. What foods should you avoid while taking Pradaxa?
Pradaxa – Foods to avoid: green leafy vegetables, vegetable oil, broccoli, cauliflower, and green tea.
3. What is the antidote for Pradaxa?
Praxbind, with the generic name idarucizumab, is the Pradaxa reversal agent. This is given to patients experiencing major bleeding.
4. What drugs should not be taken with Pradaxa?
Some medications that should be avoided while on this anticoagulant are aspirin and aspirin-containing products, warfarin, NSAIDs, heparin, and clopidogrel. These medications can further increase the risk of bleeding.
5. Is there a cheaper version of Pradaxa?
An affordable generic alternative for this product is available from Pharma Passport.
6. How much does Pradaxa cost?
You may check the pricing of this product by clicking here. Get the best deals when you purchase from Pharma Passport.
7. Is Pradaxa over the counter?
This oral anticoagulant is a prescription drug. You must present a valid prescription when purchasing this product from any pharmacy.